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Description
Ultrasound is increasingly used in point-of-care applications and has great potential to support the diagnosis of infectious diseases, especially in resource-limited settings. A cross-sectional study was performed involving 100 Malawian patients with a clinical indication for ultrasound. Furthermore, the literature on point-of-care ultrasound (POCUS) in Sub-Saharan Africa was reviewed to establish its applicability, most frequent indications, findings, and implications for treatment, and therefore relevance in POCUS curricula, with a main focus on infectious diseases. In Malawi, the main indications for ultrasound were weight loss, abdominal pain, and shortness of breath. Abnormal findings were observed in 77% of patients, the most common being enlarged abdominal lymph nodes (n = 17), pericardial effusion (n = 15), splenic microabscesses (n = 15), and pleural effusion (n = 14). POCUS led to a change in treatment in 72% of patients. The literature on the various POCUS applications used in Malawi was reviewed, including focused assessment with sonography for HIV-associated TB (FASH), heart, liver, kidney, deep venous thrombosis (DVT), and gynaecology. Based on disease prevalence, impact of POCUS on treatment, and technical difficulty, it is proposed that FASH, heart, and DVT are the most relevant POCUS applications in comparable Sub-Saharan African settings and should be incorporated in POCUS curricula. 2016 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/bync-nd/4.0/).
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Cataldo F, Chiwaula L, Nkhata M, van Lettow M, Kasende F, Rosenberg NE, Tweya H, Sampathkumar V, Hosseinipour M, Schouten E, Kapito-Tembo A, Eliya M, Chimbwandira F, Phiri S; PURE Malawi Consortium. J Acquir Immune Defic Syndr. 2017 Apr 15;74(5):517-522. doi: 10.1097/QAI.0000000000001273. PubMed PMID: 28045712; PubMed Central PMCID: PMC5340586.
3391 downloads
Wesevich A, Mtande T, Saidi F, Cromwell E, Tweya H, Hosseinipour MC, Hoffman I, Miller WC, Rosenberg NE. AIDS Care. 2017 Mar 29:1-9. doi: 10.1080/09540121.2017.1308464. [Epub ahead of print] PubMed PMID: 28355926.
3468 downloads
Kalua T, Tippett Barr BA, van Oosterhout JJ, Mbori-Ngacha D, Schouten EJ, Gupta S, Sande A, Zomba G, Tweya H, Lungu E, Kajoka D, Tih P, Jahn A. J Acquir Immune Defic Syndr. 2017 May 1;75 Suppl 1:S43-S50. doi: 10.1097/QAI.0000000000001326. Review. PubMed PMID: 28398996.
3273 downloads
Kalua T, Tippett Barr BA, van Oosterhout JJ, Mbori-Ngacha D, Schouten EJ, Gupta S, Sande A, Zomba G, Tweya H, Lungu E, Kajoka D, Tih P, Jahn A.J Acquir Immune Defic Syndr. 2017 May 1;75 Suppl 1:S43-S50. doi: 10.1097/QAI.0000000000001326. Review. PubMed PMID: 28398996.
3173 downloads
Phiri S, Tweya H, van Lettow M, Rosenberg NE, Trapence C, Kapito-Tembo A, Kaunda-Khangamwa B, Kasende F, Kayoyo V, Cataldo F, Stanley C, Gugsa S, Sampathkumar V, Schouten E, Chiwaula L, Eliya M, Chimbwandira F, Hosseinipour MC; PURE Malawi Consortium. J Acquir Immune Defic Syndr. 2017 Jun 1;75 Suppl 2:S140-S148. doi: 10.1097/QAI.0000000000001357. PubMed PMID: 28498183.
3129 downloads
Cataldo F, Sam-Agudu NA, Phiri S, Shumba B, Cornelius LJ, Foster G. J Acquir Immune Defic Syndr. 2017 Jun 1;75 Suppl 2:S224-S232. doi: 10.1097/QAI.0000000000001375. PubMed PMID: 28498193.
2985 downloads
McCarthy E, Joseph J, Foster G, Mangwiro AZ, Mwapasa V, Oyeledun B, Phiri S, Sam-Agudu NA, Essajee S. J Acquir Immune Defic Syndr. 2017 Jun 1;75 Suppl 2:S233-S239. doi: 10.1097/QAI.0000000000001364. PubMed PMID: 28498194; PubMed Central PMCID: PMC5432093.
3378 downloads
Gugsa S, Potter K, Tweya H, Phiri S, Sande O, Sikwese P, Chikonda J, O'Malley G. PLoS One. 2017 Jun 21;12(6):e0179838. doi: 10.1371/journal.pone.0179838. eCollection 2017. PubMed PMID: 28636669; PubMed Central PMCID: PMC5479573.
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Ongubo DM, Lim R, Tweya H, Stanley CC, Tembo P, Broadhurst R, Gugsa S, Ngongondo M, Speight C, Heller T, Phiri S, Hosseinipour MC.BMC Infect Dis. 2017 Jul 3;17(1):461. doi: 10.1186/s12879-017-2528-0. PubMed PMID: 28673254; PubMed Central PMCID: PMC5496231.